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COVID-19 In Vitro Diagnostic Devices and Test Methods Database

Scientific literature on COVID-19 Test Methods and Devices - detail

Comparison of Cepheid Xpert Xpress and Abbott ID Now to Roche cobas for the Rapid Detection of SARS-CoV-2

DOI
10.1016/j.jcv.2020.104428 
Detection Principle
NucleicAcid-PCR based
Target
E, N and ORF1 a/b
Testing Method Category
RT-PCR
Testing Method
Cepheid Xpert Xpress and Abbott ID Now to Roche cobas
Testing Method - Additional Info
Cepheid Xpert Xpress SARS-CoV-2 and Abbott ID Now SARS-CoV-2, to the Roche cobas SARS-CoV-2 assay for samples with low, medium, and high viral concentrations.
Reported Performance
Positive agreement compared to Cobas for ID Now: 73.9%, Positive agreement compared to Cobas for Cepheid Xpert Xpress: 98.9%. Negative agreement compared to Cobas for ID NOW: 100%, Negative agreement compared to Cobas for Cepheid Xpert Xpress: 92.0% for medium and high concentration. Ct values >30 positive agreement ID NOW: 34.3%, Ct values >30 positive agreement Cepheid Xpress Xpert:97.1%
Sample Size
Peer-reviewed
yes

The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements