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COVID-19 In Vitro Diagnostic Devices and Test Methods Database

Scientific literature on COVID-19 Test Methods and Devices - detail

A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction

Detection Principle
ImmunoAssay-Antibody
Target
total immunodominant neutralizing antibodies targeting the S protein
Testing Method Category
ELISA
Testing Method
in house ELISA
Testing Method - Additional Info
test based on antibody-mediated blockage of the interaction between the ACE2 receptor protein and the receptor-binding domain
Reported Performance
specificity: 99.93%, sensitivity: 95-100%
Sample Size
60 samples
Assay Type
 
Peer-reviewed
yes

The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements