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COVID-19 In Vitro Diagnostic Devices and Test Methods Database

Scientific literature on COVID-19 Test Methods and Devices - detail

Comparison of the analytical sensitivity of seven commonly used commercial SARS-CoV-2 automated molecular assays

Detection Principle
NucleicAcid-PCR based
multiple targets
Testing Method Category
Testing Method
Testing Method - Additional Info
Abbott Molecular RealTime SARS-CoV-2 assay (Abbott Molecular, Des Plaines, Il), NeuMoDx SARS-CoV-2 assay (NeuMoDx, Ann Arbor, Michigan), Roche Cobas SARS-CoV-2 assay, Becton Dickinson BD Max reagents (Becton Dickinson, Sparks, MD), Hologic Aptima SARS-CoV-2 assay (Hologic, Bedford, MA), Cepheid Xpert Xpress SARS-CoV-2 test (Cepheid, Sunnyvale, CA), GenMark ePlex SARS-CoV-2 test (GenMark, Carlsbad, CA)
Reported Performance
Sensitivity: 100% (Abbott), 100% (NeuMoDx, high conc), 30%-80% (NeuMoDx, low conc), 100% (roche cobas), 100% (BD max, high conc), 50%-87.5% (BD max, low conc), 100% (Hologic, high conc), 87.5% (Hologic, low conc), 100% (Xpert, high conc), 66.67%-100% (Xpert, low conc), 100% (GenMark, high conc), 33.33% (GenMark, low conc)
Sample Size
10 replicates

The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements