Comparison of seven commercial RT-PCR diagnostic kits for COVID-19
Detection Principle
NucleicAcid-PCR based
Target
E, S (Altona); ORF1ab (BGI); ORF1ab, N (CerTest); RdRP, S (KH); RdRP (PrimerDesign); E (R-Biopharm); RdRP, E, N (Seegene); E, RdRP (in house)
Testing Method Category
PCR_KIT
Testing Method
kits & in house
Testing Method - Additional Info
Altona Diagnostics, BGI, CerTest Biotec, KH Medical, PrimerDesign, R-Biopharm AG, and Seegene
Reported Performance
LOD95: 3.8 copies/mL (Altona), 4.3 (BGI), 4.8 (CerTest, N), 18 (CerTest, ORF1ab), 4.8 (KH, RdRP), 4.3 (KH, S), 23 (PrimerDesign), 4.3 (R-Biopharm), 4.8 (Seegene, E), 18 (Seegene, RdRP), 0.91 (in house PCR, E), 3.1 (in house PCR, RdRP). Remark: detection rate varies between kits, none of the assays showed cross-reactivity with other respiratory (corona)viruses, except as expected for the SARS-CoV-1 E-gene.
Sample Size
19 samples
Peer-reviewed
yes
The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements