Rapid quantification of SARS-CoV-2-neutralizing antibodies using propagation-defective vesicular stomatitis virus pseudotypes
Detection Principle
ImmunoAssay-Antibody
Target
neutralizing antibodies
Testing Method Category
Testing Method
in house (psudotyped virus) and kits (Allplex SARS-CoV-2 specific RT-qPCR assay, Seegene; RealStar SARS-CoV-2 RT-PCR Kit, Altona Diagnostic Technologies; Euroimmun AG, Lübeck, Germany # EI 2606-9601 G and # EI 2606-9601 A)
Testing Method - Additional Info
The pseudotype virus neutralization dose 50% (PVND50) and the SARS-CoV-2 neutralizing dose 50% (ND50) determined in the sera from two independent cohorts of individuals that had been tested positive for SARS-CoV-2 infection by RT-PCR and/or ELISA show good coorelation
Sample Size
29 samples
Peer-reviewed
yes
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