Monitoring antibody response following SARS-CoV-2 infection: Diagnostic efficiency of four automated immunoassays
Detection Principle
ImmunoAssay-Antibody
Target
IgM, IgG, IgA
Testing Method Category
Testing Method
CLIA, ELISA, ELFA
Testing Method - Additional Info
kits: Elecsys (Roche), Liaison S1/S2 IgG (Diasorin), IgG and IgA (Euroimmun), VIDAS IgG and IgM
Reported Performance
Sensitivity: 81.1% (Elecsys), 70.3% (Liaison), 86.5% (Euroimmun IgA+IgG), 78.4% (VIDAS IgG+IgM); Specificity: 100% (Elecsys), 100% (VIDAS); PPV: 100% (Elecsys), 100% (VIDAS)
Sample Size
111 patients & 96 controls
Peer-reviewed
yes
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