Evaluation of Nucleocapsid and Spike Protein-based ELISAs for detecting antibodies against SARS-CoV-2
Detection Principle
ImmunoAssay-Antibody
Target
IgM/IgG on N-protein, S-protein
Testing Method Category
Testing Method
ELISA multiple-kits
Testing Method - Additional Info
ELISA rN kit; Lizhu, Zhuhai, China; ELISA rS kit: Hotgen, Beijing, China
Reported Performance
Sensitivity: 77.1% (rS IgM), 74.3% (rS IgG), 68.2% (rN IgM), 70.1% (rN IgG), 82.2% (rS IgG/gM), 80.4% ( rN IgG/IgM) ; Specificity: 100% ; Remark: seven dpo groups= 0–5, 6–10, 11–15, 16–20, 21–30, 31–35, and >35 dpo
Sample Size
214 patients & 100 controls
Peer-reviewed
yes
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