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COVID-19 In Vitro Diagnostic Devices and Test Methods Database

Scientific literature on COVID-19 Test Methods and Devices - detail

Antibody Detection and Dynamic Characteristics in Patients with COVID-19

DOI
10.1093/cid/ciaa461 
Detection Principle
ImmunoAssay-Antibody
Target
IgM, IgG vs N
Testing Method Category
ELISA
Testing Method
kit (Zhuhai)
Testing Method - Additional Info
The serum SARS-CoV-2 antibodies (IgM and IgG) of the subjects were detected using a sandwich enzyme linked immunosorbent assay (ELISA kits, Livzon Inc, Zhuhai, P.R.China)
Reported Performance
sensitivity: 77.3% (IgM, confirmed COVID patients), 87.5% (IgM, suspected COVID patients) 83.3% (IgG, confirmed COVID patients), 70.8% (IgG, suspected COVID patients); specificity: 100% (IgM, confirmed COVID patients), 100% (IgM, suspected COVID patients), 95% (IgG, confirmed COVID patients), 96.6% (IgG, suspected COVID patients); PPV: 100% (IgM, confirmed COVID patients), 100% (IgM, suspected COVID patients), 94.8% (IgG, confirmed COVID patients), 85% (IgG, suspected COVID patients); NPV: 80% (IgM, confirmed COVID patients), 95.2% (IgM, suspected COVID patients), 83.8% (IgG, confirmed COVID patients), 89.1% (IgG, suspected COVID patients); consistency rate: 88.1%(IgM, confirmed COVID patients), 96.4% (IgM, suspected COVID patients), 88.9% (IgG, confirmed COVID patients), 88.1% (IgG, suspected COVID patients)
Sample Size
109 patients (8 confirmed, 24 suspected)
Peer-reviewed
yes

The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements