Combination of CT and RT-PCR in the screening or diagnosis of COVID-19
Detection Principle
mixed
Target
Testing Method Category
In_silico
Testing Method
CT imaging and RT-PCR in parallel or in series
Testing Method - Additional Info
We recommend that parallel tests are used in screening, while series tests should be used for diagnosis confirmation of COVID-19. Parallel tests perform RT-PCR and CT imaging at the same time and the results are cross-referenced to make the diagnosis. Serial test employs as a secondary screening test which is performed only if the result of initial screening test is positive.
Reported Performance
Sensitivity of chest CT imaging: 97%; specificity: 25%, with RT-PCR as a diagnosis criterion. Sensitivity of RT-PCR testing: 65%; specificity 83%, if chest CT as a reference of diagnosis standard. Remark: If both sensitivity and specificity were taken into account simultaneously, neither chest CT nor RT-PCR testing alone is accurate enough for the diagnosis of COVID-19 infection.
Sample Size
1014 patients
Assay Type
Peer-reviewed
yes
The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements