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COVID-19 In Vitro Diagnostic Devices and Test Methods Database

Scientific literature on COVID-19 Test Methods and Devices - detail

Clinical evaluation of four commercial immunoassays for the detection of antibodies against established SARS-CoV-2 infection

DOI
10.1016/j.pathol.2020.09.003 
Detection Principle
ImmunoAssay-Antibody
Target
IgG
Testing Method Category
Other Immuno assay
Testing Method
1)The Elecsys Anti-SARS-CoV-2 assay (Roche Diagnostics, Germany) 2) The Liaison SARS-CoV-2 S1/S2 IgG assay (DiaSorin, Italy) 3) The Access SARS-CoV-2 IgG assay (Beckman Coulter, USA) 4)
Testing Method - Additional Info
Comparison of clinical performance of 4 available antibody kits
Reported Performance
1) Elycsis Sensitivity: 98.84% ; Specificity: 100%; 2)Liaison Sensitivity: 96.51% ; Specificity: 97.89% ; 3) Access assay Sensitivity: 88.84%; Specificity: 98.95%; 4) Vitro assays Sensitivity: 97.67%; Specificity: 100%
Sample Size
190 sera
Peer-reviewed
yes

The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements