Immune response to SARS-CoV-2 in health care workers following a COVID-19 outbreak: A prospective longitudinal study
Detection Principle
ImmunoAssay-Antibody
Target
IgG, IgA vs S (Euroimmun); IgG, IgM, IgA vs N (Roche)
Testing Method Category
Other
Testing Method
Prospective longitudinal study
Testing Method - Additional Info
prospective study usign data provided by Ab kits: the Anti-SARS-CoV-2 IgG and IgA ELISA (EUROIMMUN AG, Lübeck, Germany) and the Elecsys Anti-SARS-CoV-2 (Roche Diagnostics, Rotkreuz, Switzerland)
Reported Performance
Remark: immune response after a COVID-19 outbreak increases significantly over time but still approximately 22% of COVID-19 patients did not mount a measurable serologic immune response within 60 days after symptoms have occurred. Exposed co-workers did not develop any relevant IgG antibody levels over time.
Sample Size
166 subjects
Peer-reviewed
yes
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