Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison
Detection Principle
ImmunoAssay-Antibody
Target
IgG
Testing Method Category
Other Immuno assay
Testing Method
1)SARS-CoV-2 IgG assay (Abbott, Chicago, IL, USA), 2) LIAISON SARS-CoV-2 S1/S2 IgG assay (DiaSorin, Saluggia, Italy), 3) Elecsys Anti-SARS-CoV-2 assay (Roche, Basel, Switzerland), 4) SARS-CoV-2 Total assay (Siemens, Munich, Germany), and 5)novel 384-well ELISA (the Oxford immunoassay)
Testing Method - Additional Info
comparison of 5 commercially available kits
Reported Performance
1) Abbott Sensitivity: 92.7%; Specificity: 99.9%; 2)DiaSorin Sensitivity: 96.2%; Specificity: 98.9%; 3)Oxford Sensitivity: 99.1%; Specificity: 99%; 4) Roche Sensitivity: 97.2%; Specificity: 99.8%; 5) Siemens Sensitivity: 98.1%; Specificity: 99.9%
Sample Size
1502 blood
Peer-reviewed
yes
The database contains available information from scientific literature that is being updated periodically. Please note that the provided information (as retrieved from analysed papers) is provided only for devices commercially available with CE-IVD mark. Acknowledgements